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Experiment Design
Optimal design of experiments

Optimal Experimental Design theory is an important branch of applied statistics. This section of the BioKin website is dedicated to the theory of optimal design, practically useful computational methods, and software tools that implement those methods.
Screening of enzyme inhibitors
A rational approach to the design of dilution series used in dose-response screening of enzyme inhibitors. The method is equally applicable to both "tight binding" and "classical" (weakly bound) enzyme inhibitors. Includes a freely accessible software tool to automatically generate dilution series based on the range of inhibition constant values for inhibitors in the screening pool.

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Sat May 28 13:09:23 2011