[task]
   data = velocity
   task = fit

; Partial noncompetitive inhibition (Segel, p. 166).
; Both inhibition constnats ('Ki') are the same.

[mechanism]
   E + S <==> ES       :    Ks    dissoc.
   ES --> E + P        :    kr

   E + I <==> EI       :    Ki    dissoc.
   ES + I <==> EIS     :    Ki    dissoc.
   EIS --> EI + P      :    kir

[constants]      ; nanomolar
   Ks = 31500
   Ki = 30 ?
   kr = 30 ?
   kir = 20 ?

[concentrations] ; nanomolar
   E = 0.5
   S = 125000

[responses]
   P = 1.0

[progress]
   rapid equilibrium

[velocities]
   variable  I   ; nanomolar
   file      ./examples/aceap1/s_125/data/s125.txt 

[output]
   directory ./examples/aceap1/s_125/output/2_noncomp/

[settings]
   <Marquardt>
      Interrupt = 200
   <Velocity>
      AverageInput = No

[end]