  |
 
|
|
|
 |
| Table 2: AB99-0564 |
| P. Kuzmic et al. (2000) Anal. Biochem., 281, 62-67. |
Table 2
Simulated and estimated values of apparent inhibition constants K using the Henderson equation (7) [7]. For details of the Monte-Carlo simulation experiments, see text in the Methods section.
|
simulated K (nM) |
fitted K (nM) |
|
average |
std.dev. |
maximum |
minimum |
|
0.01 |
0.010000 |
0.000053 |
0.010194 |
0.009791 |
|
0.1 |
0.10000 |
0.00052 |
0.10190 |
0.09799 |
|
1 |
0.9999 |
0.0052 |
1.0174 |
0.9808 |
|
10 |
9.999 |
0.049 |
10.189 |
9.831 |
|
100 |
91.8 |
575.0 |
6,804.2 |
-41,829.3 |
|
1,000 |
1,285 |
13,033 |
377,224 |
-1,220,830 |
|
10,000 |
11,643 |
3,162,220 |
22,841,200 |
-311,495,000 |
|
100,000 |
251,964 |
86,296,500 |
4,665,960,000 |
-5,939,910,000 |
|
 |
|
|
|
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|
www.biokin.com/papers/ki-auto/tab2.html
Fri Jan 29 13:19:38 2010 |
