King-Altman method

The steady-state rate equation below was derived by using the automatic method of Cornish-Bowden [Cornish-Bowden, A. (1977) Biochem. J. 165, 55-59].

IMPORTANT NOTE: This model is only applicable if all substrates, inhibitor, activators and other modifiers are present in very large excess over the enzyme catalyst.

Stoichiometric matrix

STOICH-MAT-ALL

Overall reaction

REACTION-KINGALT

Adjacency matrix

ADJAC-MAT-KINGALT

Rate equation

RATE-EQUATION-KINGALT